NAME: J. Kevin Foskett
AFFILIATION: University of Pennsylvania, Philadelphia, PA, USA
RESEARCH INTEREST: Our laboratory is interested in mechanisms of ion permeation across cell membranes and intracellular signaling, particularly in epithelial cells, and the roles of these processes in human disease. The lab has two distinct major foci of research efforts: understanding the molecular physiology of intracellular signaling by Ca2+ and defining the activities, regulation and roles of the normal and mutant cystic fibrosis gene product (CFTR)
|NAME: Colin R. Green|
AFFILIATION: University of Auckland, New Zealand
RESEARCH INTEREST: Our major interest is the role of gap junction channels in lesion spread and wound healing, and therapeutic application of gap junction channel specific modulators. Currently, we are focused primarily on hemichannel roles in mediating vascular dropout in trauma, ischemic and chronic inflammatory conditions of the brain and retina.
|NAME: Paul D. Lampe|
AFFILIATION: Fred Hutchinson Cancer Research Center, University of Washington, USA
RESEARCH INTEREST: My lab studies how signaling pathways regulate gap junctions. Specifically, we study the kinases that regulate gap junctions, the sites phosphorylated on connexins and how these events affect gap junction cell biology both in cell culture models and in mouse and human tissues (during development, wounding, ischemia and cancer).
NAME: Kodi Ravichandran
AFFILIATION: University of Virginia School of Medicine, USA
RESEARCH INTEREST: My laboratory is interested how we remove apoptotic cells in the body. Recently, we have been focusing on how apoptotic cells, via the pannexin channels, release nucleotides as a find-me signal to attract phagocytes and thereby facilitate corpse clearance.
NAME: Steven S. Segal
AFFILIATION: University of Missouri & Dalton Cardiovascular Research Center, USA
RESEARCH INTEREST: My laboratory is focused on understanding the nature of cell-to-cell signaling along the endothelium and between the endothelium and smooth muscle cells of vascular resistance networks in light of how such interactions are regulated by perivascular sympathetic nerves.
NAME: Gina Sosinsky
AFFILIATION: University of California, San Diego, School of Medicine
RESEARCH INTEREST: My current research focuses on the high resolution structure of connexins and pannexins and their in situ arrangements in the plasma membrane, trafficking structures and internal organelles in cells and tissues. To accomplish these goals, we use a variety of imaging techniques that span spatial domains from sub-nanometer to microns.