|NAME: Glenn I. Fishman|
AFFILIATION: New York University School of Medicine, USA
RESEARCH INTEREST: My lab studies cardiac electrophysiology and mechanisms of arrhythmias. We are particularly interested in studies of cardiac conduction system development and disease, as well as gap junction remodeling and disease.
|NAME: Steven Poelzing|
AFFILIATION: University of Utah, USA
RESEARCH INTEREST: My lab is interested in the mechanisms of electrical impulse formation and failure in the heart. In particular, we seek to understand how cellular coupling through gap junctions and the extracellular matrix mediates the electrical spread of propagation.
|NAME: Matthias M. Falk|
AFFILIATION: Lehigh University, USA
RESEARCH INTERESTS: Of particular interest to me are processes related to protein biosynthesis, intracellular trafficking, the assembly of multi-protein complexes, and how cells in a multi-cellular organism communicate with each other. We use molecular biology, biochemistry, and in particular live-cell imaging approaches to investigate how cells regulate and modulate gap junction mediated direct cell-cell communication (GJIC), as well as physical cell-cell adhesion.
|NAME: Hung-I Yeh|
AFFILIATION: Mackay Medical College, Taiwan
RESEARCH INTEREST: My lab is interested in the role of gap junction and connexin in human cardiovascular disease. In particular, in atherogenesis and arrhythmogenesis. Currently we examine connexins in regulation of both native cardiovascular cells and circulating progenitor cells.
|NAME: Silvia Penuela|
AFFILIATION: University of Western Ontario, Canada
RESEARCH INTEREST: My research focuses on the characterization of pannexin channels in health and disease. We are currently studying the role of pannexins in skin differentiation and malignant transformation, as well as their regulation of cartilage and bone development.
NAME: Joëlle Amedee Vilamitjana
AFFILIATION: University of Bordeaux, Inserm U1026, France
RESEARCH INTEREST: My lab is interested in strategies for improving tissue regeneration of bone and vessels with the help of human adult stem cells associated with three dimensional matrices. The cell to cell communication plays a key role in the mechanisms of tissue regeneration. In particular, we are focused on the cocultures of human mesenchymal stem cells and endothelial progenitor cells in matrices for increasing both osteogenesis and vascularization of tissues produced in 3D. The role for connexins (Cx), mainly Cx43, and cadherins in mediating osteogenesis and vascularization are particularly targeted in our research.
|NAME: Steffany Bennett|
AFFILIATION: University of Ottawa, Canada
RESEARCH INTEREST: My laboratory studies the role connexins and pannexins play in adult neurogenesis, gliogenesis, central nervous system (CNS) injury, and CNS repair. In particular, we focus on modulating the repertoire of connexin/pannexins expressed by CNS cells and/or their channel-dependent and channel-independent functions to reduce cell loss and direct appropriate cell replacement.
NAME: Roger Thompson
AFFILIATION: University of Calgary, Canada
RESEARCH INTEREST: My lab is interested in the physiology and pathophysiology of pannexin-1 in the brain. We are exploring the roles of pannexin in neuronal death during stroke and in synaptic physiology.
|NAME: Brenda Kwak|
AFFILIATION: University of Geneva Medical School, Switzerland
RESEARCH INTEREST: My lab is interested in the function of connexins in cardiovascular physiology and pathology. In particular, we focus on the regulation of connexins by shear stress and role of connexins in the pathogenesis of atherosclerosis, thrombosis and reperfusion injury.
|NAME: Viviana M. Berthoud|
AFFILIATION: University of Chicago, USA
RESEARCH INTEREST: I am interested in many aspects of the regulation of gap junctions. The main focus of my research is on the mechanisms by which mutant lens connexins lead to cataract formation.
|NAME: Cor de Wit|
AFFILIATION: Universität zu Lübeck, Germany
RESEARCH INTEREST: My lab studies intercellular communication in the blood vessel wall. We are focused on identifying connexins that allow either longitudinal (along the veesel) or transversal (from the endothelium to the smooth muscle) communication using mice that lack different connexins and studying their vessel function by intravital microscopy.
|NAME: Luc Leybaert|
AFFILIATION: Ghent University, Belgium
RESEARCH INTEREST: My lab is interested in the role of connexin and pannexin channels in cell death communication, calcium waves/oscillations, cardiomyocyte function/dysfunction and blood-brain barrier regulation. We have specific focus on hemichannels.
|NAME: Masahito Oyamada|
AFFILIATION: Fuji Women's University, Japan
RESEARCH INTEREST: My lab is interested in the interaction of nutrition with connexin expression. In particular, we are focused on the epigenetic regulation of connexins in various organs under low/high nutrient conditions.
|NAME: Robin Shaw|
AFFILIATION: University of California-San Francisco, USA
RESEARCH INTEREST: My lab is interested in the trafficking of cardiac gap junction proteins to the plasma membrane. In particular, we are focused on how Cx43 based channels use the microtubule and actin cytoskeleton to arrive at gap junctions, and how they are subsequently removed.
|NAME: Peter R. Brink|
AFFILIATION: Stony Brook University, USA
RESEARCH INTEREST: Research Interests: My lab has focused on the delivery of gene products in stem cells to target cells both in vivo and in vitro where delivery is mediated by gap junctions. We use a combination of methods to assess delivery viability including dual whole cell patch clamp, FACS sorting, Gene Chip analysis and proteomics. Examples of gene products are currents generated by membrane channels expressed in stem cells that then flow into target cells or the production of siRNAs to silence genes in target cells.